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medRxiv PreprintsInternational5 November 2026

Divergent Causes of Death After Ischemic and Hemorrhagic Stroke in the Reperfusion Era: A Contemporary Cohort Study

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Background: Contemporary data on long-term, cause-specific mortality among stroke survivors are sparse, and much of the existing evidence derives from studies performed before the modern reperfusion era. We sought to characterize long-term cause-specific mortality among stroke survivors to discharge (differentiated by stroke subtype) when compared to in-hospital stroke decedents treated under contemporary standards of care. Methods: Using a hybrid billing-code/imaging and large language model-assisted chart-review pipeline, we identified adults hospitalized for ischemic or hemorrhagic stroke i
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