Decision-Making Under Stress, Biological Stress Responses, and Risk for Suicidal Behavior in Young Adults

Background: Stress may influence decision-making processes relevant to suicidal behavior, yet few studies have examined risky decision-making and expected value (EV) sensitivity under stress longitudinally among young adults at elevated suicide risk. Methods: Participants included 233 young adults (18-30 years) with recent suicide attempts (n=55), suicidal ideation (n=59), psychiatric controls (n=71), and healthy controls (n=48). Hair cortisol concentration, circulating inflammatory markers (CRP, IL-6, IL-10, IL-1ra, TNF-alpha), Stressful Cups Task, and clinical measures were assessed at basel

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