Clinical and Social Determinants of Guideline-Directed Medical Therapy Optimization in Heart Failure with Reduced Ejection Fraction

Background: Heart failure with reduced ejection fraction (HFrEF) is associated with high morbidity and mortality. Guideline-directed medical therapy (GDMT) for HFrEF has been shown to improve outcomes, with higher GDMT scores at hospital discharge being associated with lower mortality, fewer rehospitalizations and reduced healthcare costs. Yet, disparities in the utilization of GDMT remain. In this study, we examined the effect of various clinical, demographic, and socioeconomic factors on the utilization of GDMT in HFrEF patients referred to Cardiology in a tertiary care safety net hospital,

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