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medRxiv PreprintsInternational2 November 2026

Chronic health conditions, multimorbidity and subsequent economic inactivity in three British birth cohorts

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Background. Economic inactivity due to ill-health has been rising in the United Kingdom. Chronic health conditions make up most of the burden of poor health, and frequently co-occur, yet the impact of multimorbidity on economic inactivity remains underexplored. Methods. Data was from three British birth cohorts (born in 1946, 1958 and 1970). Psychological distress, chronic back pain and cardiometabolic disease were assessed in participants' thirties and forties, and economic inactivity one to two decades later. Modified Poisson regression models with robust standard errors estimated associatio
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