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medRxiv PreprintsInternational2 November 2026

Associations Between Cannabis Use and Sleep Outcomes in a Sample of Pregnant Women

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Importance. Both sleep difficulties and cannabis use during pregnancy (CUP) are common and associated with adverse birth and offspring outcomes. Sleep problems are a commonly reported motive for cannabis use during pregnancy. Objective. Estimate associations between cannabis use during pregnancy and common sleep difficulties across trimesters. Design, Setting, and Participants. This cohort study recruited pregnant women with lifetime cannabis use who used (n=298) and did not use (n=143) cannabis during pregnancy. Women who reported heavy episodic alcohol consumption or use of other illicit sub
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