medRxiv PreprintsInternational1 November 2026
ASSESSING THE ACCEPTABILITY OF, AND WILLINGNESS TO PAY FOR, EVENT-DRIVEN PRE-EXPOSURE PROPHYLAXIS AMONG CISGENDER MEN IN CAPE TOWN, SOUTH AFRICA
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Introduction: South Africa has expanded access to pre-exposure prophylaxis (PrEP), yet men remain under-represented. Event-driven pre-exposure prophylaxis (ED-PrEP), taken around episodes of sexual activity, offers an effective non-daily option for cisgender men with intermittent sexual exposure. However, evidence on ED-PrEP in South Africa remains limited. We assessed ED-PrEP awareness and understanding, acceptability and willingness to pay (WTP) among cisgender men in Cape Town, South Africa. Methods: We conducted a cross-sectional survey among 150 cisgender men attending community-based mob
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