Anatomical comparison populations and threshold transport in vascular transcriptomic classification

Background: High vascular transcriptomic discrimination may obscure dependence on comparison populations, gene selection, and score scale. We examined these properties separately. Methods: GSE100927 compared surgical atherosclerotic tissue with lesion-free deceased-donor arteries: 104 arrays formed 95 complete-label groups, versus 96 arteries reported originally; independent donor identities remained unresolved. Within held-out folds, pooled area under the receiver-operating-characteristic curve (AUROC) was decomposed into nine case-bed-control-bed comparisons. Seven fixed rules underwent ten

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