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medRxiv PreprintsInternational1 November 2026

Agreement of abdominal palpation with point-of-care ultrasound for hepatosplenic organomegaly: a cross-sectional, population-based study in schistosomiasis-endemic settings of rural Uganda

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Background: Ultrasound is commonly used to assess hepatosplenic morbidity in schistosomiasis, but access may be limited in resource-constrained settings. Abdominal palpation is simple and inexpensive, yet its clinical value and diagnostic performance for detecting ultrasound-defined organ enlargement remains uncertain. We evaluated standardised abdominal palpation against point-of-care ultrasound in a schistosomiasis-endemic setting in rural Uganda. Methods: We conducted a cross-sectional study in January-February 2024 of 3177 participants aged 5-92 years from Pakwach, Buliisa and Mayuge distr
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