Announcements tracker
What health authorities announced
1,950 announcements from official sources, each one linking straight to the document that issued it. We record what was announced and who announced it. We do not rewrite it.
- medRxiv PreprintsInternational2 Oct 2026
Exploring Ensemble Selection for Model Averaging in Model-informed Precision Dosing: A Tacrolimus Case Study Extended to Cefepime and InfliximabExploring Ensemble Selection for Model Averaging in Model-informed Precision Dosing: A Tacrolimus Case Study Extended to Cefepime and Infliximab
Model averaging combines the predictions of several population pharmacokinetic models to support model-informed precision dosing, but how to select ensemble models remains unexplored. Using tacrolimus as a case study,…
- medRxiv PreprintsInternational2 Oct 2026
Reliability and accuracy of medication-based performance measures for assessment of outpatient cardiology clinicians
Background: Multiple performance measures are used to assess the management of common cardiovascular conditions, such as coronary artery disease (CAD), heart failure with reduced ejection fraction (HFrEF), and atrial…
- medRxiv PreprintsInternational2 Oct 2026
Rare Germline Variants and Genetic Susceptibility to Pleural Mesothelioma: Moving Beyond DNA Repair
A minority of asbestos-exposed individuals develop Pleural mesothelioma (PM), suggesting a role for inherited genetic factors. We performed germline whole-exome sequencing of blood from 127 EPIC participants who…
- medRxiv PreprintsInternational2 Oct 2026
Interaction Between Exercise Intensity and Sedentary Behavior on VO2max Change in Patients with De Novo Parkinson Disease: The Study in Parkinson Disease of Exercise (SPARX) Phase 2 Randomized Clinical Trial
Background Parkinson disease (PD) is associated with increased sedentary time and reduced cardiorespiratory fitness, making exercise an important component of disease management. Although exercise improves…
- arXiv — AI in Healthcare (preprints)International1 Oct 2026
Fusing Visual and Textual Representations via Multi-layer Fusing Transformers for Vietnamese Visual Question Answering
In recent decades, artificial intelligence has made significant progress in understanding and interacting with images. One of the important applications of this technology is Visual Question Answering (VQA), a research…
- medRxiv PreprintsInternational1 Oct 2026
An explainable multimodal framework for exploring depression-associated speech representations in Alzheimer's disease
Depression in Alzheimer's disease (AD) is clinically challenging to characterise because affective and cognitive manifestations frequently overlap with the underlying neurodegenerative condition. This study investigates…
- medRxiv PreprintsInternational1 Oct 2026
A modified Delphi study to determine Australian healthcare consumer priorities and consensus for the use of genomics and precision medicine approaches in pregnancy healthcare and research
Background: Pregnancy is a uniquely complex ethical and clinical context in which precision medicine approaches, including genomics-driven risk prediction tools, biomarker-based stratification, and data-intensive…
- medRxiv PreprintsInternational1 Oct 2026
Time-aware machine learning enables early intrapartum identification of fetuses at risk of hypoxic-ischemic encephalopathy from cardiotocography
Cardiotocography (CTG) is the standard of care for intrapartum fetal monitoring, yet its poor specificity drives unnecessary intervention without reducing hypoxic-ischemic encephalopathy (HIE). Most artificial…
- medRxiv PreprintsInternational1 Oct 2026
An auditable multimodal agentic system for sequential decision-making across the acute stroke pathway
Ischemic stroke is a leading cause of long term disability worldwide. Although timely reperfusion can improve outcomes, realizing this benefit requires clinicians to integrate fragmented clinical and imaging information…
- medRxiv PreprintsInternational1 Oct 2026
Impact of Daily Physical Fatigue on Inter-Limb Load Asymmetry and Joint Loading Rates During Daily Living Tasks in Unilateral Knee Osteoarthritis
Background: Knee osteoarthritis (OA) is characterized by progressive joint degradation and altered gait biomechanics. Inter-limb load asymmetry during daily living tasks may accelerate joint deterioration, particularly…
- medRxiv PreprintsInternational1 Oct 2026
Comprehensive proteomic characterization of the esophageal String Test identifies a luminal protein signature associated with eosinophilic esophagitis.
ABSTRACT Background: The esophageal String Test (EST) is emerging as a minimally invasive alternative for assessing disease activity in eosinophilic esophagitis (EoE), yet the molecular composition of its protein…
- medRxiv PreprintsInternational1 Oct 2026
Modelling the influence of the duration of effectiveness and time taken to implement vector control interventions for vector-borne diseases.
Implementing vector control interventions against infectious diseases is operationally challenging, with delivery and population uptake taking considerable time within a community. Studies have suggested that the slow…
- medRxiv PreprintsInternational1 Oct 2026
Increasing risks of recurrence following community-associated Clostridioides difficile infection in Oxfordshire 2000-2025
Background Clostridioides difficile infections (CDI) continue to cause substantial morbidity and mortality, with increasing incidence in some countries post-COVID-19. Recurrence affects 10-20% of CDI patients: whether…
- medRxiv PreprintsInternational1 Oct 2026
Design and outcome-model estimability in doubly robust survival analysis: a breast cancer reanalysis
Doubly robust survival estimators require nuisance models that the available information can support. We examine design and estimator dependence in TCGA breast cancer data. Treatment indicators disagree for 337 of 1076…
- medRxiv PreprintsInternational1 Oct 2026
Functional connectivity correlates of post-acute covid 19 cognitive and neuropsychiatric complications
Abstract Background The neuropsychiatric sequelae (cognitive deficits, anxiety and depression) post-COVID-19 exist as part of the spectrum of the multisystemic long COVID. People with these symptoms have been shown to…
- medRxiv PreprintsInternational1 Oct 2026
Clinical and Radiomics Predictors of Post-stroke Longitudinal Mortality: A Prospective Cohort Study from a Tertiary Care Hospital in India
Background: Stroke imposes substantial mortality and socioeconomic burden in India, particularly among younger adults. However, prospective evidence on the prognostic value of baseline clinical and radiomics features…
- medRxiv PreprintsInternational1 Oct 2026
Surgical Performance and Patient Outcomes in Robot-Assisted Esophagectomy: A Crowd-Sourced Video-Based Assessment
Background: Robust evidence linking individual surgeon technical performance to patient outcomes in complex minimally invasive surgery remains scarce. Crowd-sourced video assessment offers a scalable alternative to…
- medRxiv PreprintsInternational1 Oct 2026
Diabetes related antibody signature highlights ZnT8 as a novel antigenic target in rheumatoid arthritis
Objective: Autoantibodies are central for pathology of rheumatoid arthritis (RA) and diabetes mellitus (DM) carrying high predictive and diagnostic value. Here, we explore the frequency and functional potential of…
- medRxiv PreprintsInternational1 Oct 2026
The Effects of a Digital Exercise Therapy Application for Patients with Shoulder and Knee Pain During the COVID-19 Pandemic
Objective: To examine changes in function and pain interference among patients utilizing a digital exercise therapy application (DETA) for knee and shoulder pain. Methods: We conducted a retrospective analysis of data…
- medRxiv PreprintsInternational1 Oct 2026
Hemodynamic Responses to Cold Water Ingestion During Head-Up Tilt
Purpose We examined whether drinking a small volume of cold water during orthostatic stress attenuates the fall in systolic blood pressure (SBP). Methods In a randomized crossover study, 19 healthy young adults…
- medRxiv PreprintsInternational1 Oct 2026
Early imaging signs associated withsubsequent diagnosis of primary sclerosingcholangitis
BACKGROUND Primary sclerosing cholangitis (PSC) is characterized by multifocal biliary strictures on MRI/MRCP. However,we have observed that young PSC patients often displayed a marked intrahepatic bile duct…
- medRxiv PreprintsInternational1 Oct 2026
An Epidemiological Study of the Impact of Doula Care on Black Birth Outcomes in Baltimore, Maryland
This study examines the impact of various maternal factors and continuous labor support on birth outcomes among 124 birthing people in the Baltimore region of Maryland who sought and/or received doula care. The cohort…
- medRxiv PreprintsInternational1 Oct 2026
Perspectives from EPI personnel on immunization programme performance in Kenya: a thematic, complex adaptive systems and leverage-points analysis
Abstract Immunisation system performance depends on effective service delivery and the generation of high-quality data to support planning and decision-making. With the recent scaling down of external health funding,…
- medRxiv PreprintsInternational1 Oct 2026
1Hz vs. cTBS Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics: A Randomized Clinical Trial
Background: Response to Comprehensive Behavioral Intervention for Tics (CBIT), the first-line treatment for tic disorders, is suboptimal. We conducted Phase 1 of a two-phase, milestone-driven trial to determine if…
- medRxiv PreprintsInternational1 Oct 2026
Adolescent-Reported National Norms, Psychometrics, and Clinical Considerations for the Nationwide Quality of Life Scale (NQLS)
Abstract Objective: The Nationwide Quality of Life Scale (NQLS) is a brief, public-domain, youth self-report measure designed for quality of life (QoL) reporting in measurement-based care (MBC). Preliminary psychometric…
- medRxiv PreprintsInternational1 Oct 2026
Multivariate neural signatures of worry become more differentiated across adolescence and young adulthood: An ultra-high field (7T) fMRI study
Worry is an important contributor to anxiety and depressive disorders, particularly in adolescence. Underlying changes in brain networks are thought to drive development of pathological worry, yet the degree to which…
- medRxiv PreprintsInternational1 Oct 2026
Exploring associations between trust in doctors and the likelihood of accessing healthcare for anxiety, depression and menstrual problems
Background Anxiety, depression and menstrual problems are conditions that significantly impact an individual's health and wellbeing yet, barriers to healthcare can prevent access to appropriate medical care. Trust in…
- medRxiv PreprintsInternational1 Oct 2026
Methylation-associated Gene Expression (MaGE): a non-invasive, in vivo measure of cellular senescence.
Cellular senescence is a central hallmark of aging, yet its measurement in humans remains invasive, low-throughput and tissue-specific, precluding population-scale study. We developed Methylation-associated Gene…
- medRxiv PreprintsInternational1 Oct 2026
Triangulating population, individual, and genetic evidence for priority setting in structurally heterogeneous blocs: metabolic risk factors for stroke in the Shanghai Cooperation Organisation
BACKGROUND: Regional stroke-prevention priorities usually rest on what a bloc's members share. Where members span multiple Global Burden of Disease (GBD) super-regions and genetic ancestry groups, population,…
- medRxiv PreprintsInternational1 Oct 2026
Blood Pressure Reduction in Multiomic Digital Food-as-Medicine: a single-arm cohort study with a regression-to-the-mean-adjusted estimand
Elevated systolic blood pressure (SBP) is a major modifiable driver of cardiovascular morbidity. Digital food-as-medicine and home-blood-pressure-monitoring programs increasingly support its management outside the…
- medRxiv PreprintsInternational1 Oct 2026
THE CARDIO-PAL SCORE - A NOVEL PROGNOSTICATION TOOL FOR 6-MONTH MORTALITY IN HEART FAILURE INPATIENTS
Background: Patients with heart failure (HF) experience high mortality, yet survival estimates remain challenging. Available prognostic tools commonly predict survival beyond 1-year, limiting goals of care discussions…
- arXiv — AI in Healthcare (preprints)International30 Sept 2026
From Knowledge to Legitimacy: A Philosophical Problem Discovery of AI Implementation Readiness in Public Health Disease Surveillance
Despite being an emerging credible means of using artificial intelligence (AI) for improving disease surveillance via early detection of outbreaks, epidemics prediction and evidence-based decision-making, there continue…
- arXiv — AI in Healthcare (preprints)International28 Sept 2026
Structural Alignment for Reliable Industrial AI: Bridging Physical Reality, Data, Models, and Human Intent
Artificial intelligence is increasingly deployed in critical industrial domains, including healthcare, energy grids, subsurface exploration, where failures can have severe consequences for human safety, system…
- arXiv — AI in Healthcare (preprints)International28 Sept 2026
Applying Language Models in Clinical Medicine: Recent Trends and Perspectives
The use and applicability of artificial intelligence (AI) in medical research and clinical practice has received increasing attention in the literature over recent years. The emergence of large language models (LLMs)…
- arXiv — AI in Healthcare (preprints)International27 Sept 2026
T-MoXAI: A Hierarchical Explainability Framework for Temporal Multimodal Data
Artificial Intelligence (AI) models for temporal multimodal data have potential in healthcare and agriculture, but their opacity can limit trust and adoption. We introduce T-MoXAI (Temporal Multimodal eXplainable AI), a…
- arXiv — AI in Healthcare (preprints)International18 Sept 2026
A Sociotechnical Review of Algorithms in Health Systems: Technical, Cost, and Human-Centered Considerations
Artificial intelligence (AI) applications in healthcare are becoming increasingly prevalent, to assist health systems, providers, and patients with tasks such as decision-making, risk prediction, and diagnosis. This…
- arXiv — AI in Healthcare (preprints)International17 Sept 2026
AI Smart Glasses for Wearable Intelligence: From Egocentric Sensing to Agentic Personalization
Recent advances in artificial intelligence (AI) are reshaping smart glasses from egocentric capture and display devices into platforms for wearable intelligence. Smart glasses increasingly serve as wearable AI systems…
- arXiv — AI in Healthcare (preprints)International16 Sept 2026
Prepared Or Unprepared? Evaluating Healthcare Workforce Readiness for Clinical Adoption of Artificial Intelligence in Nigeria
Artificial intelligence (AI) is increasingly integrated into healthcare systems worldwide, yet its successful clinical adoption depends critically on workforce readiness, particularly in low- and middle-income countries…
- arXiv — AI in Healthcare (preprints)International16 Sept 2026
A Comprehensive Review of Generative Physical Artificial Intelligence
The integration of large-scale foundation models with physical embodiments has led to significant advancements in robotics known as Generative Physical Artificial Intelligence (GPAI). These agentic AI systems…
- arXiv — AI in Healthcare (preprints)International14 Sept 2026
Mapping U.S. Federal AI Governance Against Sector Vulnerability
Artificial intelligence (AI) poses different levels of risk across sectors, but are these differences reflected in U.S. federal AI governance? To help answer this question, we assess 684 federal AI governance documents…
- arXiv — AI in Healthcare (preprints)International13 Sept 2026
AI Deployment Accountability Engineering: A Vision for Accountable AI in Safety-Critical Socio-Technical Systems
Artificial intelligence systems are rapidly becoming critical components in healthcare, finance, public services, and other safety-critical domains. Yet the engineering practices used to evaluate these systems remain…
- arXiv — AI in Healthcare (preprints)International13 Sept 2026
Mobile CT Services for Rural, Regional, and Remote Areas: Current Practice and Future Integration with Telehealth and Regulatory-Authorised AI
Computed tomography (CT) plays an essential role in clinical workflow to improve patient outcomes. However, access to CT imaging and specialist interpretation remains limited, particularly in rural, regional, remote…
- arXiv — AI in Healthcare (preprints)International10 Sept 2026
Differentially Private EEG Feature Anonymization: A Privacy-Utility Case Study in Clinical Neurophysiology
Clinical electroencephalography (EEG) data are valuable for healthcare research and for developing artificial intelligence (AI)-based clinical decision-support systems, but EEG recordings and derived features may…
- arXiv — AI in Healthcare (preprints)International8 Sept 2026
Assessment of Non-Institutional AI Tool Usage Among Clinicians
Generative artificial intelligence (AI) tools are increasingly accessible and have the potential to improve efficiency across clinical workflows. However, clinicians may also use non-institutional AI tools that are not…
- arXiv — AI in Healthcare (preprints)International8 Sept 2026
Healthcare Utilization, Chronic Condition Management, and Workplace Functioning Among Users of a Purpose-Built Mental Health AI (Ash): Cross-Sectional Study
Mental health challenges can exacerbate physical symptoms and complicate management of chronic conditions. Purpose-built artificial intelligence (AI) tools may offer scalable support for co-occurring mental and physical…