medRxiv PreprintsInternational6 October 2026
U-shaped effects of humidity and the impact of misspecified weather-transmission relationships in epidemic models
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Understanding the relationship between weather conditions and infectious disease transmission has important public health implications; nevertheless, the functional form of this relationship often remains poorly understood. Humidity has previously been suggested to have a U-shaped effect on the transmission of respiratory pathogens, with optimal transmission occurring at both low and high levels. Here, to assess the impact of this functional form and of its potential misspecification, we first simulate transmission rates based on the U-shaped relationship and then test whether an exponential f
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