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medRxiv PreprintsInternational7 October 2026

The Lost Glucose Sink: Association of Sarcopenia Risk with Disproportionate Postprandial Glycemic Excursions in Older Adults with Type 2 Diabetes Mellitus

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Abstract Background: Many adults with type 2 diabetes mellitus (T2DM) in India have a thin fat body type, with low skeletal muscle mass for their body mass index. Muscle is the main site of glucose disposal after a meal. Fasting blood sugar (FBS) mostly reflects glucose output from the liver, whereas postprandial blood sugar (PPBS) depends more on insulin driven glucose uptake by muscle. Objective: To show how the association between sarcopenia risk and postprandial glycemic excursion would be tested in older adults with T2DM and controlled fasting glucose. Methods: A cross sectional design is
— medRxiv Preprints
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