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medRxiv PreprintsInternational5 October 2026

Radiofrequency Catheter Ablation of Atrial Fibrillation in Patients with Anomalous Pulmonary Venous Return: A Multicenter Case Series.

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Background: Atrial fibrillation (AF) has been observed in adults with anomalous pulmonary venous return (APVR), but data on catheter ablation outcomes in this population remain limited to case reports and small series. Methods: We retrospectively reviewed 14 adult patients with confirmed APVR who underwent catheter ablation for AF at three tertiary academic centers in the United States between July 2003 and May 2025. Baseline, procedural, electroanatomic mapping, and outcome data were collected. Freedom from atrial arrhythmia recurrence was estimated by Kaplan-Meier analysis. Results: Mean age
— medRxiv Preprints
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