Myocardial Perfusion in Patients with Primary Mitral Regurgitation Due to Mitral Valve Prolapse

Background: Mitral regurgitation (MR) is a common complication of mitral valve prolapse (MVP) and increases left ventricular (LV) preload, promotes LV remodeling and hypertrophy, but its impact on myocardial perfusion and coronary microvascular dysfunction remains unclear. Objectives: To assess myocardial perfusion using, for the first time, quantitative cardiac magnetic resonance (CMR) perfusion mapping in patients with significant MR due to MVP. Methods: Patients with significant primary MR, without coronary artery disease were prospectively enrolled and compared to age- and sex-matched cont

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