Metabolic profiling reveals heterogeneity within childhood obesity phenotypes

Background & Aims: Childhood obesity is a complex, heterogeneous disease. Children with obesity are often grouped into metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) phenotypes, although this classification may oversimplify the underlying metabolic diversity. We aimed to characterise the metabolic profiles associated with the conventional MHO/MUO classification and to identify data-driven metabolic profiles in 267 children and adolescents with obesity. Methods: In this cross-sectional study, we used serum 1H-NMR spectroscopy to quantify lipoproteins, glycoprotein

This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program — especially if you are pregnant, nursing, taking medication, or managing a health condition.