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medRxiv PreprintsInternational16 October 2026

LUCID: Lipid-featured Urine Cytology with Intelligent Detection for Non-Invasive Early Diagnosis of Bladder Cancer

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Firsthand records what medRxiv Preprints announced and links to the original. The wording below is theirs, not ours.

Leveraging its non-invasive and convenient nature, urinary cytology offers a way for the early diagnosis and surveillance of bladder cancer (BCa). However, its sensitivity remains substantially inferior to the histopathological gold standard, rendering it inadequate to support precise clinical diagnosis. Here, we developed Lipid-featured Urine Cytology with Intelligent Detection (LUCID), an automated platform integrating single-cell stimulated Raman scattering (SRS) imaging and explainable AI model for accurate BCa detection. Following a newly developed standardized urine-preprocessing protoco
— medRxiv Preprints
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