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medRxiv PreprintsInternational16 October 2026

Mechanisms of action of a community-led HIV prevention and treatment programme for female sex workers in Zimbabwe: a mixed-method analysis

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Background Community-led interventions for female sex workers (FSW) can improve HIV prevention and treatment outcomes by lowering self-stigma and strengthening social cohesion to improve service uptake. In Zimbabwe, the AMETHIST intervention trial integrated peer-led microplanning with self-help groups for FSW and demonstrated improved HIV treatment outcomes. We investigated the role of social cohesion and self-stigma in explaining these findings. Method We conducted a mixed-method analysis of data collected during AMETHIST. We re-analysed qualitative data from interviews and group discussions
— medRxiv Preprints
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