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medRxiv PreprintsInternational16 October 2026

Heart rate variability and electrocardiographic parameters among workers exposed to chronic intermittent hypobaric hypoxia in the Peruvian Andes: A cross-sectional study Cardiac autonomic function in Andean workers

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Chronic intermittent hypobaric hypoxia is an occupational exposure experienced by workers who alternate between high-altitude worksites and lower-altitude resting locations. Its effects on cardiac autonomic modulation and electrocardiographic parameters remain insufficiently characterized in Andean workers. This study aimed to compare heart rate variability and electrocardiographic parameters between workers exposed to chronic intermittent hypobaric hypoxia and controls working permanently at lower altitude in Arequipa, Peru. An observational cross-sectional study was conducted in 96 male work
— medRxiv Preprints
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