medRxiv PreprintsInternational6 October 2026
Healthcare providers perceptions of barriers and facilitators to implementation of an acute traumatic brain injury clinical practice guideline: a CFIR-informed qualitative study at a regional referral hospital in Northern Tanzania
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Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality in low- and middle-income countries (LMICs), where the burden of injury is disproportionately high, and healthcare resources are often limited. Clinical Practice Guidelines (CPGs) improve the consistency and quality of TBI care by shifting medical decision-making from individual judgement to evidence-based recommendations. The strong link between improved TBI outcomes and CPG adoption has largely been established in high-income country (HIC) hospital settings; evidence on implementing TBI CPGs in LMIC hospital
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