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medRxiv PreprintsInternational11 October 2026

A Multi-Domain EEG Framework Integrating Spectral, Functional Connectivity, and Topological Features for Subject-Level ADHD Classification

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Background: Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by persistent symptoms of inattention, hyperactivity, and impulsivity that significantly affect cognitive, academic, and social functioning. Although electroencephalography (EEG) has emerged as a promising non-invasive tool for identifying objective neurophysiological biomarkers of ADHD because of its high temporal resolution and cost-effectiveness, many existing machine learning studies rely on single-domain EEG features, which may not adequately capture the complex functional org
— medRxiv Preprints
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