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medRxiv PreprintsInternational11 October 2026

A lay teacher-counsellor delivered brief psychological treatment for moderate to severe depression among older adolescents in senior high schools in Ghana (Y-MIND): a feasibility cluster randomized controlled trial

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Introduction: Adolescents experience high rates of depression and anxiety, yet globally 80% of adolescents and almost all in low-and middle-income countries (LMICs) lack access to adolescent-friendly treatments. The African Youth in Mind (Y-MIND) set out to adapt the youth version of the Friendship Bench and assess its feasibility for delivery in Ghana. Methods: In this feasibility cluster randomised controlled trial, we recruited participants aged 15 to18 years with probable diagnosis of moderate to severe depression ascertained with the Patient Health Questionnaire (PHQ-9) total score > 9 fr
— medRxiv Preprints
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