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medRxiv PreprintsInternational2 October 2026

Time-Varying Coactivation Pattern and Knee Joint Kinematics and Kinetics Following ACL Reconstruction: A Statistical Parametric Mapping Approach

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Introduction: Knee muscle coactivation is elevated after anterior cruciate ligament reconstruction (ACLR), contributing to altered joint loading and post-traumatic osteoarthritis. Existing methods average coactivation within predefined gait phases and require priori designation of muscles roles, limiting the resolution for when differences occur. Objective: Characterize knee joint coactivation and dynamics throughout gait in individuals with ACLR using statistical parametric mapping. Methods: Ten individuals with unilateral ACLR and ten healthy matched controls performed overground walking at
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