Sex differences in depression and substance use disorder diagnoses and overdose risk in British Columbia

Background: Depression is a risk factor for overdose and is more commonly diagnosed among females. However, sex-differences in the association between depression, in isolation and in combination with substance use disorder (SUD), and overdose have not been examined at the population level in British Columbia (BC). This study described sex-and-age differences in associations between documented history of depression and/or SUD diagnoses and risk of fatal (FOD) and non-fatal overdose (NFOD). Methods: This study used linked administrative health data from the Provincial Health Services Authority P

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