Predicting One-Year CPAP Adherence and Use Trajectories Utilizing Baseline and Early Use Data

Introduction Maintaining long-term positive airway pressure (CPAP) adherence is a major challenge when treating obstructive sleep apnea (OSA). We evaluated factors associated with one-year CPAP adherence and developed models predicting Month-12 adherence and CPAP-use trajectories. Methods CPAP-naive adults with OSA (apnea-hypopnea index[≥]5) at Kaiser Permanente Southern California with 364-day observation period were analyzed (development/internal-validation cohort, n=14,906; temporal holdout, n=1,676). Logistic regression evaluated baseline associations with Month-12 adherence (mean[≥]

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