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medRxiv PreprintsInternational13 October 2026

Patterns and correlates of alcohol and other substance use among adults in two communities in Cape Town: a cross-sectional

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Background We aimed to characterize substance use patterns, and their correlates, among adults with and without HIV at two healthcare facilities in Cape Town, South Africa. Methods We recruited adults with and without HIV from two primary healthcare facilities. We assessed alcohol use with the AUDIT-C and other substance use with the WHO-ASSIST questionnaires. We classified participants with no lifetime drug use and no or low-risk alcohol use as "low risk" and fitted latent class models among remaining participants to identify additional substance use patterns. We used multinomial logistic reg
— medRxiv Preprints
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