Multivariate neural signatures of worry become more differentiated across adolescence and young adulthood: An ultra-high field (7T) fMRI study

Worry is an important contributor to anxiety and depressive disorders, particularly in adolescence. Underlying changes in brain networks are thought to drive development of pathological worry, yet the degree to which neural correlates of worry vary by age is unknown. Here, we use multivariate pattern analysis (MVPA) to investigate individual variance in brain activity during worry in a cross-sectional sample of adolescents and adults varying in worry symptoms. Participants (n=69; ages 12-31) completed a personalized worry-induction fMRI task. Brain activity was averaged across k=268 brain regi

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