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medRxiv PreprintsInternational1 October 2026

Modelling the influence of the duration of effectiveness and time taken to implement vector control interventions for vector-borne diseases.

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Implementing vector control interventions against infectious diseases is operationally challenging, with delivery and population uptake taking considerable time within a community. Studies have suggested that the slow mass drug administration (MDA) of the endectocide, ivermectin, may have contributed to the lower epidemiological impact against malaria observed in recent cluster-randomised controlled trials, although evidence supporting this hypothesis is lacking. It is unclear whether interventions which have short but highly effective durations of entomological impact are more impactful than
— medRxiv Preprints
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