medRxiv PreprintsInternational14 October 2026
Individual Angiotensin Receptor Blockers and Risk of Dementia: A Target Trial Emulation Study
This is an official announcement record
Firsthand records what medRxiv Preprints announced and links to the original. The wording below is theirs, not ours.
INTRODUCTION: Observational studies suggest that angiotensin receptor blockers (ARBs) are associated with lower dementia risk than angiotensin-converting enzyme inhibitors (ACEIs). Whether dementia risk differs across individual ARBs remains uncertain and was investigated in this study. METHODS: This retrospective cohort study emulated target trials using electronic health record and claims data from 44 US health care organizations in the TriNetX Linked Research Network. ACEI/ARB-naive adults aged 55 to 80 years initiating an ARB or lisinopril were eligible. Separate 1:1 propensity-score match
Read the official announcement
Opens www.medrxiv.org
More from medRxiv Preprints
- OSS-DBS v2: Simulation Platform for Biophysical Modelling of Deep Brain Stimulation14 October 2026
- A Growing Burden, a Persistent Gap: Cannabinoid Hyperemesis Syndrome Education and Emergency Department Trends in Michigans Legal Cannabis Market14 October 2026
- Enhanced local synchronization with impaired large-scale recruitment of NREM slow waves in pediatric disorders of arousal14 October 2026
- Bench Testing of an 8 N Slip Resistance Specification for the Handle Shaft Locking Interface of an Articulated Laparoscopic Instrument14 October 2026
- Neurophysiological monitoring of sport related concussion: From diagnosis to return to play14 October 2026
This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program — especially if you are pregnant, nursing, taking medication, or managing a health condition.