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medRxiv PreprintsInternational15 October 2026

IMPACT OF CENTRALIZED NIKSHAY ON TB NOTIFICATION AND DATA COMPLETENESS IN INDIGENOUS TRIBES: A 21-YEAR STUDY

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BACKGROUND: Indigenous tribes face a disproportionately high tuberculosis (TB) burden due to deep-rooted socioeconomic disadvantage, highlighting the need for strengthened, culturally sensitive control strategies. METHODS: We conducted a 21-year retrospective study (2005-2025) among tribal and neighboring non-tribal populations attending a tribal-serving hospital in Karnataka. Pre-Nikshay data were transcribed from paper registers, and post-Nikshay data were obtained from the digital system. We assessed negative binomial interrupted time-series regression model, data completeness, TB risk fact
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