medRxiv PreprintsInternational15 October 2026
High Intensity Focused Ultrasound (HIFU) Thalamotomy as a Safe and Effective Treatment of Essential Tremor (ET) in Older Populations and those with Comorbidities
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Magnetic Resonance guided High Intensity Focused Ultrasound (MRgHIFU) has been demonstrated to be a safe and effective minimally invasive therapy for essential tremor (ET). However, it is not clear whether older adults ([≥]70 years old) or individuals with comorbidities exhibit similar safety and efficacy. This IRB approved project collected EPIC EMR data on patients that underwent MRgHIFU at Parkview Regional Medical Center from January 2023 to November 2025. 68 patients were assessed for tremor severity using Clinical Rating Scale for Tremor (CRST), quality of life using Quality of life i
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