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medRxiv PreprintsInternational2 October 2026

Description of the APOLLO Registry: Integrated Cardio-Renal Perfusion Assessment and Cardiometabolic Phenotyping Using Cardiac 82Rb-PET/CT

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Background: Cardiovascular, kidney, and metabolic diseases are closely interconnected and may share common pathophysiological mechanisms, including microvascular dysfunction. Although cardiac 82Rb-PET/CT is routinely used for myocardial perfusion imaging, its potential for integrated cardio-renal perfusion assessment and cardiometabolic phenotyping remains underexplored. We recently developed a compartment modelling approach to quantify renal perfusion from routine cardiac 82Rb-PET/CT, enabling simultaneous assessment of cardio-renal perfusion. However, real-world imaging registries integratin
— medRxiv Preprints
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