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medRxiv PreprintsInternational14 October 2026

Deep Learning and Radiomics Models for Predicting 90-Day Outcomes in Ischemic Stroke: A Systematic Review and Meta-Analysis

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Background Accurate prediction of 90-day outcomes following ischemic stroke is crucial for optimizing clinical strategies. This study aimed to systematically review and meta-analyze studies using deep learning (DL) and hand-crafted radiomics (HCR) models for predicting 90-day modified Rankin Scale (mRS) outcomes after ischemic stroke. Methods We followed the PRISMA guidelines for systematic reviews. Four databases (PubMed, Embase, Web of Science, and Cochrane Library) were searched comprehensively for studies published up to September 2025. Inclusion criteria encompassed original research focu
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