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medRxiv PreprintsInternational12 October 2026

ClinStigma: A Clinician-Guided Framework for Developing Synthetic Benchmarks of Contextual Stigmatizing Language in Clinical Documentation

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Objective Large language models (LLMs) are increasingly used to generate, summarize, and evaluate clinical documentation, yet standardized methods for evaluating nuanced, context-dependent clinical language remain limited. Existing approaches rely primarily on annotated clinical corpora or keyword-based methods, restricting reproducibility, public dissemination, and systematic comparison across models. We present ClinStigma, a clinician-guided framework for constructing, annotating, and evaluating synthetic benchmarks of contextual stigmatizing language, demonstrated through ClinStigma-SUD, it
— medRxiv Preprints
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