medRxiv PreprintsInternational12 October 2026
Clinical Epistemic Reopening: When Patient Reality Makes Medical Framing Reconsiderable
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Modern clinical medicine depends on reducing complex human realities into forms that support knowledge, judgment, and action. Such reduction is indispensable to scientific medicine, but necessarily selective. A medical framing may therefore remain well warranted within medicine while becoming insufficient in relation to the reality of a particular patient. What happens clinically when the adequacy of such a framing itself becomes uncertain remains insufficiently understood. We conducted an abductive, theory-generating qualitative study of 44 patients who attended a supplementary Dialogue-Based
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