Attenuated alpha state transitions and disrupted repetition-dependent temporal adaptation in mild cognitive impairment

Mild cognitive impairment (MCI) may involve impaired dynamic regulation of brain states that is not captured by conventional resting-state electroencephalography (EEG). We quantified occipital alpha (8-12 Hz) transitions during three repeated eye-opening/eye-closure cycles in 60 healthy controls (HC) and 77 participants with MCI. Eye-state events were refined from frontal ocular artifacts. Transition magnitude was measured by the log-transformed post-/pre-event energy ratio, and transition success by the expected direction of alpha change. For canonical transitions meeting prespecified fit-qua

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